Sr Application Specialist **Apply for Job** **Job ID** 24662 **Location** Toronto, Ontario **FTE** 1.00 **Annualized Hiring Range** $85,455 - $117,500 **Contract Length** *Compensation commensurate with experience **Level of Police Check** Criminal & Judicial Record **Date Posted** 2026-11-04 **Deadline to Apply** 2026-11-18 **Dept/Program Name** Research Information Technolog **Target Openings** 1 **Work Type** Hybrid **Hours of Work** 35.00 **Add to Favorite Jobs** **Email this Job** **About Sick

Kids** Dedicated exclusively to children and their families, The Hospital for Sick Children (Sick

Kids) is one of the largest and most respected paediatric healthcare centres in the world.

As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education.

Our reputation would not have been built - nor could it be maintained - without the skills, knowledge and experience of the extraordinary people who come to work here every day.

Sick

Kids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.

When you join Sick

Kids, you become part of our community.

We share a commitment and determination to fulfill our vision of _Healthier Children. A Better World_ .

Don't miss out on the opportunity to work alongside the world's best in paediatric healthcare. **Position Description** Sick

Kids' Research Institute is modernizing its technology infrastructure to advance clinical research across the institution.

Established in 2024 and aligned with Sick

Kids' enterprise-wide

Clinical Research Strategy (https://www.sickkids.ca/siteassets/about/strategy--performance/supporting-strategies/clinical-research-strategy.pdf) , the Clinical Research Technology Program (CRTP) is building a regulatory-ready and sustainable digital ecosystem for clinical research.

Technology will serve as a catalyst for connection, efficiency, and innovation by strengthening compliance and oversight, improving data integrity, streamlining research workflows, expanding patient participation, and enabling greater integration between research and care.

As part of this work, the CRTP is introducing new clinical research platforms at Sick

Kids, beginning with Electronic Data Capture (EDC) and electronic Trial Master File / electronic Investigator Site File (eTMF/eISF).

Additional platforms related to the CRTP roadmap may be explored in the future.

We are seeking a Senior Clinical Research Application Specialist to configure, support, and maintain the validated state of these new platforms.

As a senior member of the Research IT Application Support team, you will serve as the primary application administrator for EDC and eTMF/eISF, leading configuration, change control, and validation activities in close partnership with vendors, Clinical Research Operations, and Research IT colleagues.

This is a new role that will evolve over the next two to three years as the portfolio expands and the supporting team grows. **Here's What You'll Get to Do** Application Configuration and Change Management Collaborate with vendors and internal teams to plan, review, test, and implement configurations, integrations, and releases across the EDC and eTMF/eISF platforms.

Translate clinical research, regulatory, privacy, security, and operational needs into clear technical and configuration requirements.

Review vendor-proposed solutions and configurations for alignment with approved requirements, intended use, and Sick

Kids standards.

Serve as the primary technical contact with vendors for configuration questions, defects, and support escalations.

Manage application changes through Sick

Kids change control processes.





Assess vendor releases and upgrades for impact on configuration, workflows, and validated state, and coordinate regression testing.

Maintain configuration specifications and change records to support audit readiness.

Validation Support Review vendor validation packages, and support validation planning and execution.

Support user acceptance testing, including evidence collection, defect management, and deviation documentation.

Maintain the validated state through documented testing, change control, release-impact assessments, regression testing, periodic review support, and controlled deployment practices.

Maintain current validation and technical documentation for internal governance, sponsors, auditors, and other partners, as required.

Lead the development, review, implementation, and ongoing maintenance of system administration and operational standard operating procedures (SOPs) across the clinical research technology portfolio.

Application Support and Ongoing Operations Lead technical troubleshooting during implementation, validation, UAT, go-live, and ongoing operations, coordinating escalation across vendors and relevant internal teams.

Support operational processes for application administration, access management, incident and request management, vendor escalation, release management, and service reporting.

Investigate incidents, identify root causes, coordinate solutions, and monitor recurring issues, application performance, support trends, and improvement opportunities.

Develop system administration procedures, support guides, knowledge articles, configuration specifications, and application-specific standard operating procedures.

Monitor application usage, operational performance, vendor support, service needs, and improvement opportunities to inform product planning and the clinical research technology roadmap. **Here's What You'll Need** To be successful in this role, we are seeking someone with the following: Bachelor's degree in health informatics, information systems, computer science, health sciences, or a related discipline, or an equivalent combination of education and experience.

Five or more years of experience implementing, configuring, validating, administering, or supporting enterprise applications in healthcare, research, life sciences, or another regulated environment.

Hands-on administration experience with at least one clinical research platform (e.g., EDC, eTMF/eISF) or a comparable regulated application.

Demonstrated experience across application implementation and operations, including configuration, integration, testing, troubleshooting, change control, and release management.

Experience with computerized system validation and maintaining validated applications, including risk-based testing, validation documentation, and audit readiness.

Knowledge of clinical research workflows, including CRF design, query management, data integrity, and role-based access principles.

Strong analytical, problem solving, and written communication skills.

Ability to work independently, exercise sound judgment, and establish sustainable practices in an evolving service environment.

Demonstrated commitment and actions in advancing equity, diversity, and inclusion objectives You should highlight if you have: Experience with EDCeTMF/eISF,or comparable clinical research platforms.

Knowledge of GAMP 5, 21 CFR Part 11,



Health Canada expectations, electronic records and signatures, audit trails, and risk-based validation.

Experience with SaaS applications, identity and access management, APIs, system integrations, and reporting tools.

Experience in a hospital, academic research, clinical research, or life-sciences environment.

Experience supporting audit- or inspection-ready systems and documentation. **About the Team:** Research IT is a collaborative team delivering project, product, application, and technical services across the Sick

Kids Research Institute.

Our diverse technology environment offers meaningful opportunities to solve complex challenges, develop new capabilities, and grow alongside supportive colleagues.

We value collaboration, professional development, work-life balance, and flexible hybrid work.

As a senior member of the Application Support team, you will help shape a current clinical research technology service and build sustainable capabilities that enable research innovation and advance Sick

Kids' vision of Unprecedented Outcomes Powered by

Precision Child Health (https://www.sickkids.ca/en/about/precision-child-health/) . **Here** **'** **s What You** **'** **ll Love** This position is eligible for employee benefits coverage including but not limited to; health, dental and life insurance.

The full benefits package will be discussed at the time of offer. A focus on employee wellness with our new Staff Health and Well-being Strategy (https://2025.sickkids.ca/staffwellbeing/) .

Self-care helps us support others. A hospital that welcomes and focuses on Equity, Diversity, and Inclusion (https://2025.sickkids.ca/edi/) .

The opportunity to make an impact.

Regardless of your role or professional interest, you will be making a difference at Sick

Kids and contributing to our vision of Healthier Children. A Better World.

For more on why you'll love working at Sick

Kids, visit our careers site (https://www.sickkids.ca/en/careers-volunteer/careers/) . **Employment Type:** Permanent full-time 35 hours/week **Our Commitment to Diversity** Sick

Kids is committed to championing equity, diversity and inclusion in all that we do, fostering an intentionally inclusive and culturally safe environment that reflects the diversity of the patients, families and communities we serve.

Learn more about workplace inclusion. (https://www.sickkids.ca/en/about/edi/workplace-inclusion/) **Accessibility & Accommodation** If you require accommodation during the application process, please reach out to our aSKHR team ( [email protected] ) .

Sick

Kids can provide access and inclusion supports to eligible candidates to support their full engagement during the interview and selection process as well as to ensure candidates are able to perform their duties once successfully hired.

If you are invited for an interview and require accommodation, please let us know at the time of your invitation to interview.

Information received related to access, inclusion or accommodation will be addressed confidentially. **How To Apply** Technical difficulties? Email [email protected] with a short description of the issues you are experiencing.

We will not accept resumes sent to this inbox but we are happy to respond to requests for technical assistance. **Tip:** Combine your cover letter and resume into **ONE** document of 20 pages or less as you cannot upload multiple documents as part of your application.

Every application is reviewed by a human recruiter and all hiring decisions are made by people.

In some cases, AI-assisted tools are used to help review applications based on job-related qualifications.

All positions posted on the Sick

Kids Hospital's Careers Site represent current vacancies, unless otherwise posted in the job description.

📌 Sr Application Specialist (Toronto)
🏢 SickKids
📍 Toronto