Optimize engineered VLP production in yeast through bioreactor runs and process-variable testing. Apply rigorous bench skills to improve yields and recovery.

As a senior research associate, you will test growth media, induction strategy, temperature, harvest time, and related variables. You will run yeast expression in shake flasks and small-scale bioreactors. The work includes purification, concentration, routine QC, stability screening, and troubleshooting across production workflows.

Key Responsibilities:

Optimize media, induction, temperature, and harvest conditions

Run shake-flask and small-scale bioreactor production

Perform harvest, lysis, clarification, and purification workflows

Evaluate particle assembly, purity, aggregation, and RNA integrity

Troubleshoot yield,



recovery, stability, and QC inconsistencies

Requirements:

BSc or MS in biochemistry, biotechnology, or related discipline

Experience expressing biological products in yeast or microbes

Experience with small-scale fermentation or bioreactor runs

Working knowledge of SDS-PAGE, Western blot, ELISA, qPCR, HPLC/SEC, or DLS

Exact technique and reproducible execution of small experiments

Use yeast bioprocessing, purification, and analytical QC expertise to improve engineered VLP production and particle quality.

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📌 Biochemistry Research Assistant (Toronto)
🏢 Molagri
📍 Toronto