Are you looking for an opportunity to advance cutting-edge research that supports public health, emergency preparedness, and scientific innovation? Can you see yourself working at the intersection of radiation biology, bioengineering, and organ-on-a-chip technologies to develop next-generation models for radiation injury and recovery? If you answered yes, this may be the opportunity for you. Apply today, as our Chalk River Laboratories location is looking for a Postdoctoral Fellow Researcher to support pioneering research in organ-on-a-chip systems, biodosimetry, radiation countermeasures, and radiobiology.

What you will be doing

- Establishing methods to develop 3D co-culture for creating physiologically relevant in vitro models.
- Sourcing and cell culture preparation.
- Method Establishment & Optimization.
- Culture Maintenance & Scaling.

- Evaluating biomarkers of radiation exposure and tissue injury.

- Biomarker Identification and Validation.
- Tissue Injury Model Evaluation (i.e., building multivariate algorithms and organ-specific diagnostic models using proteomic platforms to differentiate between total-body and partial-body exposures).
- Assessing the feasibility of translating candidate biomarkers into deployable devices or point-of-care assays for mass casualty mass screenings.

- Microfluidic Device optimization and testing.

- Collaborating with experts in microfluidics supporting organ-on-a-chip design.
- Collaborating with engineering and science teams to ensure the microfluidic chip works seamlessly.
- Testing and validating the designed chips for organ-on-a-chip irradiation and culture.

- Data Collection, Analysis, and Assay Development.

- Performing high-resolution imaging, viability testing, and molecular assays to assess the functional outcomes of the models.
- Running statistical models and applying statistical methods to identify meaningful trends, patterns, and correlations.




- Completing validation and troubleshooting of established assays.

- Other duties as assigned by your manager.

What we are looking for:

- Education
- PhD in Radiation Biology, Biomedical Engineering, Bioengineering, Cell Biology, Microfluidics, Biophysics, Biotechnology, or a related field.

- Experience

- 2 to 3 years of experience in cell and/or molecular biology, with good writing skills exemplified by reports and both internal and external publications.
- Experience mentoring junior researchers, training undergraduate students, or laboratory technicians.
- Past involvement in writing grant proposals or seeking external funding is a major asset.
- Experience in organ-on-a-chip, microfluidics, tissue engineering, or advanced in vitro models is a plus.
- Experience working with ionizing radiation systems and radiation biology assays.
- Experience with biomarker discovery platforms including omics technologies and extracellular vesicles.
- Experience with statistical analysis and computational data interpretation.

- Knowledge, Skills & Abilities

- Demonstrated experience with cell culture and mammalian in vitro systems.
- Familiarity with biomarkers of radiation exposure.
- Excellent written and verbal communication skills.
- Ability to work independently and collaboratively in a multidisciplinary environment.
- Familiarity with biodosimetry or radiation countermeasure research.
- Knowledge of microfabrication, 3D bioprinting, biosensors, or imaging techniques.

- Security Clearance Eligibility Required

- Reliability Status with Site Access Security Clearance (SASC), which has a minimum requirement of 3-5 years of verifiable history in Canada, Australia, Current Zealand, the United States and/or the United Kingdom. CNL implements security screening in accordance with the Treasury Board of Canada Secretariat's “Standard on Security Screening” and the “Policy on Government Security.”

Working Conditions:

- Working schedule: Five (5) days per week, seven and a half (7.5) hours per day for a thirt

📌 Postdoc: Organ-on-Chip (Chalk River)
🏢 CANADIAN NUCLEAR LABORATORIES
📍 Chalk River