Design novel drug candidates remotely from South Africa using organic synthesis and structure-activity relationship expertise. Advance small molecule discovery through rigorous chemistry.

This senior medicinal chemistry position focuses on small molecule drug discovery within pharmaceutical research and development. You will design, synthesize, and optimize lead compounds while collaborating with biologists, pharmacologists, and computational chemists. Your work supports novel therapeutic candidates and unmet medical needs.

Key Responsibilities:

- Design and synthesize novel small molecule compounds
- Optimize lead compounds through iterative SAR cycles
- Characterize compounds using NMR, LC-MS, and HPLC
- Interpret biological data with collaborating scientists
- Prepare reports for presentations and publications

Requirements:

- PhD in organic or medicinal chemistry
- At least five years industry medicinal chemistry experience
- Expertise in asymmetric and multi-step synthesis
- Experience designing diverse chemical libraries
- Robust SAR and structure-based drug design understanding

Apply senior medicinal chemistry expertise across synthesis, characterization, SAR, and remote small molecule drug discovery research.

📌 Senior Medicinal Chemistry Scientist (Kimberley)
🏢 Placements24
📍 Kimberley