Principal Scientist, Bioanalytical R&D; – LC-MS/MS Method Development

Employment Type: Full-time, Permanent

About the Opportunity

Groom & Associés is currently partnering with an established organization in the pharmaceutical and biotechnology research sector to recruit an experienced Principal Scientist, Bioanalytical R&D; – LC-MS/MS.

This is an exciting opportunity for an accomplished scientific professional to take a leadership role within a GLP-compliant bioanalytical laboratory, overseeing method development, driving scientific innovation, and leading a specialized Research & Development team.

The successful candidate will combine deep technical expertise in LC-MS/MS bioanalysis with strong scientific leadership, project oversight, and the ability to collaborate across research, operations, and commercial functions.

Key Responsibilities

Scientific Leadership & Method Development

- Lead bioanalytical R&D; activities, including LC-MS/MS method development for small and large therapeutic molecules.
- Develop innovative analytical methodologies and oversee the implementation and verification of client methods.
- Serve as the principal scientific expert for LC-MS/MS method development and complex analytical challenges.
- Review and approve R&D; reports, analytical methods, and scientific data prior to transfer for GLP validation or submission to sponsors.
- Ensure scientific excellence, data integrity, and compliance with applicable GLP standards and internal procedures.
- Stay current with emerging technologies, regulatory developments, and industry best practices.

Team Leadership & Operational Collaboration





- Lead, mentor, and develop a specialized team of R&D; scientists.
- Oversee departmental activities, project priorities, resource allocation, and scientific deliverables.
- Support recruitment, onboarding, and professional development within the R&D; department.
- Collaborate closely with GLP Operations, Method Validation, and Mass Spectrometry teams to ensure successful project execution.
- Identify opportunities to improve laboratory efficiency, scientific capabilities, and departmental performance.

Scientific Strategy & Client Collaboration

- Act as a key scientific resource for internal stakeholders and external clients.
- Provide technical expertise during project feasibility assessments, scientific discussions, and proposal development.
- Partner with Business Development and commercial teams to evaluate new opportunities, project timelines, and technical requirements.
- Contribute to project quotations, resource estimates, and scientific budget planning.
- Support strategic scientific partnerships and represent the organization at relevant industry events and conferences.

Qualifications & Experience

- Master's degree or Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences,



or a related scientific discipline.
- Minimum 8–10 years of experience in an LC-MS/MS bioanalytical laboratory operating within a GLP-compliant environment.
- At least 5 years of experience in Research & Development, with significant involvement in bioanalytical method development.
- Advanced technical expertise in LC-MS/MS, analytical chemistry, and bioanalytical assay development.
- Experience working with small molecules and/or large therapeutic molecules.
- Strong understanding of GLP requirements, method validation, and analytical data integrity.
- Demonstrated ability to lead scientific projects, resolve complex technical challenges, and collaborate with multidisciplinary teams.
- Previous team leadership or scientific management experience is strongly valued.
- Excellent organizational, problem-solving, and stakeholder management skills.

What We Offer

- 3–4 weeks of vacation, depending on experience.
- 7 personal/sick days annually.
- Group insurance following the probationary period.
- Employer RRSP matching contributions of up to 3%.
- Monday-to-Friday schedule, 36.25 hours per week.
- Opportunity to lead scientific innovation within a specialized bioanalytical research environment.

Why Consider This Opportunity?

This position offers the opportunity to play an influential role in shaping scientific strategy, developing cutting-edge bioanalytical methodologies, and contributing to the growth of an established research organization.

For an experienced LC-MS/MS scientist seeking greater scientific owner

📌 Principal Scientist, Bioanalytical R&D – LC-MS/MS Method Development (Canada)
🏢 Groom & Associés / Associates
📍 Canada