About the Role

Our client, a leading pharmaceutical research company, is seeking a talented Senior Organic Chemist to join their innovative drug discovery team in Kimberley, Northern Cape . This role is essential for the synthesis of novel small molecules and the optimization of lead compounds. You will work in a state-of-the-art laboratory, applying advanced synthetic methodologies to tackle complex chemical challenges. The position requires a deep understanding of organic chemistry principles, reaction mechanisms, and contemporary synthetic techniques. This hybrid role allows for focused lab work and strategic planning, contributing to the development of life-saving therapeutics within a collaborative and scientifically rigorous environment.

Key Responsibilities

- Design and execute multi-step synthesis of complex organic molecules.
- Optimize reaction conditions to improve yield, purity, and efficiency.
- Characterize synthesized compounds using spectroscopic techniques (NMR, MS, IR).
- Develop robust and scalable synthetic routes for potential drug candidates.
- Troubleshoot synthetic challenges and propose innovative solutions.
- Collaborate with medicinal chemists, biologists, and analytical chemists.
- Maintain accurate laboratory notebooks and document experimental procedures.
- Stay updated on the latest advances in organic synthesis and medicinal chemistry.
- Present research findings at internal meetings and scientific conferences.




- Ensure compliance with laboratory safety protocols and quality standards.

Requirements

- Ph.D. in Organic Chemistry or a closely related field.
- Minimum of 5 years of post-doctoral experience in synthetic organic chemistry, preferably in the pharmaceutical industry.
- Proven expertise in designing and executing complex organic syntheses.
- Strong understanding of reaction mechanisms, stereochemistry, and asymmetric synthesis.
- Proficiency in modern spectroscopic and chromatographic techniques for compound characterization.
- Experience with reaction optimization and scale-up considerations.
- Excellent problem-solving, analytical, and organizational skills.
- Strong written and verbal communication skills.
- Ability to work independently and manage multiple projects simultaneously.
- Experience with medicinal chemistry principles is highly desirable.
- Familiarity with process chemistry is a plus.

Benefits

- Our client offers a competitive salary, a comprehensive benefits package including health insurance and retirement contributions, and performance-based bonuses. Employees have access to extensive professional development resources, including training programs and opportunities to attend scientific conferences. The hybrid work model in Kimberley, Northern Cape offers a blend of focused laboratory work and strategic planning. Join a company dedicated to scientific excellence and making a significant impact on global health.

📌 Senior Organic Chemist (Kimberley)
🏢 Placements24
📍 Kimberley