Real World Biostatistician - RWA CMH experience (hiring in Canada and US)Syneos Health is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver - for one another, our customers, and, most importantly, for those in need.technical and therapeutic area training; We are committed to building an inclusive culture - where you can authentically be yourself. We are continuously building the company we all want to work for and our customers want to work with. Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.Job ResponsibilitiesJob DescriptionBiostatistician - Real-World Evidence (RWA)Role OverviewWe are seeking a biostatistician with solid experience in real-world data (RWD) with observational study design and safety study experience in addition to RWA CMH experience.



This role will focus on the design, analysis, and interpretation of observational studies using EMR and claims data to inform: clinical development, HEOR, regulatory strategy, and market access.Key ResponsibilitiesDesign and execute real-world evidence (RWA) studies using EMR and claims data; Conducting data specs, SAP and protocol with key research objectivesDevelop and apply robust statistical methodologies, including:survival analysis; random forest)Trial emulation frameworksExternal control arm development and borrowing strategiesPerform data analysis using healthcare coding systems (e.g., D. in Biostatistics, Statistics, Epidemiology, or related field 5 years of experience in RWA/RWD analytics (industry or equivalent)Strong experience with EMR and/or claims dataProficiency in healthcare coding systems (e.g., ICD, NDC)Programming expertise in at least one of: SAS, R, or PythonWorking knowledge with SQL logic and OMOP data structuresSolid understanding of:Causal inference methodsObservational study designSample size and power considerationsSome examples: Independently write cohort definitions in SQL logic; Debug data issues e.g.,



Translate statistical estimand censoring rule and data extraction logicRWE CMH ExperiencePreferred QualificationsPh.Trial emulation methodologiesExternal control borrowing / hybrid designsBasic machine learning methods applied to RWDDemonstrated ability to work across multiple therapeutic areas (TAs) in a fast-paced environmentStrong communication and stakeholder engagement skillsAdvanced (nice-to-have, not always required)Build reusable cohort pipelinesOptimize queries for large-scale databasesWork across multiple CDMs (OMOP, Sentinel, PCORnet)Core CompetenciesAnalytical rigor and methodological depthCross-functional collaborationAbility to operate with agility across diverse projects and therapeutic areasClear and effective scientific communicationGet to know Syneos HealthOver the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.Further, nothing contained herein should be construed to create an employment contract. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

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📌 Biometric Research Scientist (Ottawa)
🏢 Syneos Health
📍 Ottawa