Academic Job CategoryFaculty Non BargainingJob ProfilePostdoctoral Research FellowJob TitlePostdoctoral Research FellowDepartmentMaxwell Laboratory | Department of Paediatrics | Faculty of MedicineCompensation RangeSee details below.Posting End DateNovember 4, 2026Note: Applications will be accepted until 11:59 PM on the Posting End Date.This position is subject to the satisfactory completion of required background checksJob End DateOctober 11, 2027This position is subject to the satisfactory completion of required background checks.
Postdoctoral Fellow Position - Cell Division and Mammary/Epithelial/Immune Cancer BiologyMaxwell Lab | BC Children's Hospital Research Institute | University of British Columbia
Position Summar yThe Maxwell Laboratory invites applications for a highly motivated Postdoctoral Fellow with strong expertise in mammary gland biology, epithelial tissue organization and immune interactions, or mechanisms of cell division and mitosis, with a particular interest in cancer susceptibility and prevention.
The successful candidate will have an excellent publication track record and will join a dynamic research team focused on understanding how errors in cell division and tissue organization contribute to hereditary and childhood cancers, with emphasis on BRCA1-associated pathways, spindle orientation, and epithelial cell fate decisions in mammary and related tissues.
About the Lab The Maxwell Lab, led by Dr. Chris Maxwell at BC Children's Hospital Research Institute and UBC, investigates how cell division is regulated at the molecular and tissue level, and how its disruption alters epithelial - immune interactions that contribute to hereditary cancers and pediatric malignancies (https://bcchr.ca/maxwell-lab).
Mechanisms of cell division fidelity, spindle orientation,



and cell polarity
Role of BRCA1 and associated pathways in mammary epithelial biology
Development of in vivo and ex vivo models of pediatric and hereditary
cancers
Translation toward personalized medicine approaches in pediatric and hereditary cancers
The lab has extensive expertise in:
Human primary epithelial cell systems
Mouse and genetically engineered models
High-content and live-cell imaging
Tumor evolution and therapeutic response modeling
Research Environment The fellow will be embedded in a highly collaborative environment within BC Children's Hospital Research Institute, UBC Department of Pediatrics, and the Michael Cuccione Childhood Cancer Research Program. The lab also actively collaborates with national and international partners in the fields of: Pediatric and hereditary cancer biology and modeling; Oriented cell division mechanisms; and Precision oncology initiatives.
Project Focus (Representative Areas) and Responsibilities Applicants may contribute to one or more of the following:
Epithelial cell fate and division orientation Mechanisms controlling symmetric vs asymmetric division
Role of spindle orientation in differentiation and tumor initiation

Epithelial - immune cell interactions in hereditary cancer syndromes Functional consequences of BRCA1 pathway perturbation
Novel strategies for cancer prevention





Cell division regulation in epithelial tissue architecture
Translational cancer modeling Patient-derived mammary epithelial systems
In vivo modeling of cancer predisposition states

The fellow will be responsible for conducting basic/translational research in one or more of the above research focus areas, design and execute research plans and perform data analyses, contribute to writing manuscripts and grants, present research findings in internal and external meetings, and mentor junior trainees in the laboratory.
Required qualifications PhD in Cell Biology, Cancer Biology, Developmental Biology, Biochemistry,or related field. The ideal candidate should have obtained their PhD withinthe last 2 years and possess the ability to work independently anddemonstrate creativity.
Strong expertise in at least one of the following:Epithelial biology or organoid systems; Epithelial-Immune cell interactions;Cell division / mitosis / spindle dynamics
Proven record of first-author publications in high-impact journals
Experience with at least one of the following:Live-cell imaging or advanced microscopy; Mouse models or genetically engineered systems; Primary cell culture or organoid systems; Molecular perturbation (CRISPR, RNAi, etc.)
Preferred qualifications Background in epithelia - immune interactions
Experience in epithelial polarity or tissue architecture
Demonstrated ability to lead projects independently
Willingness to respect diverse perspectives, including perspectives in conflict with one's own.
Demonstrates a commitment to enhancing one's own awareness,knowledge, and skills related to equity, diversity, and inclusion.
What We Offe r Chance to work on fundamentally important quest

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📌 Postdoctoral Research Fellow (British Columbia)
🏢 UBC
📍 British Columbia