The Senior Manager, Commercial Operations leads the operating rhythm, governance, and cross-functional execution that enable the effectiveness of the Canadian commercial organization and broader LOC. The role translates enterprise and LOC priorities into an integrated operating plan, creates the forums and accountability mechanisms that turn priorities into action, and helps leaders make timely, well-informed decisions. Operating with considerable autonomy and solid business judgment, the role serves as the operational right hand to the Head of Commercial & Marketing Operations and a strategic partner to Business Unit and cross-functional leaders.

LOC operating rhythm and governance: designing and running the planning and performance-management cadence, including leadership agendas, monthly performance forums, decision and action documentation, and follow-through. Launch readiness and cross-functional delivery: standing up and integrating the Canada launch team, implementing the enterprise Launch Excellence playbook, and maintaining momentum until accountability is transitioned to the Senior Marketing Engagement Lead at the appropriate stage. The role does not own Business Unit strategy, performance analytics, or customer-engagement content.

Instead, the role brings these inputs together through disciplined governance, clear ownership, and effective decision-making so commercial teams can execute against Takeda’s evolving operating model and deliver stronger outcomes for patients and the business.

Reports to: Head of Commercial &

• Marketing Operations 0 (leads through matrix, project, and relational leadership) LOC operating model, planning cadence & governance Lead the end-to-end operating cadence for the commercial organization, including annual and quarterly planning, leadership team agenda development, monthly commercial performance reviews, and cross-functional governance meetings. Manage governance calendars, meeting objectives, pre-reads, decision-ready materials, action logs, and follow-up activities so forums drive decisions and execution rather than status reporting alone. Build and maintain an integrated view of priority commercial initiatives, including scope, milestones, dependencies, resources, risks, issues, decision points, and accountable owners. Partner with functional and Business Unit leaders to prioritize trade-offs using criteria aligned to LOC objectives, patient impact, business value, capacity, and compliance requirements. Performance management,



decision effectiveness & accountability Establish and operate the monthly commercial scorecard review in partnership with Insights &

• Analytics, Marketing leadership, Sales leadership, and other relevant parties. respectfully challenge performance narratives that are not supported by data or execution evidence. Execute the enterprise Launch Excellence strategy and planning framework for Takeda Canada launches, in partnership with the Marketing &

• Commercial Excellence (MCE) Launch Excellence team and local Business Unit leadership. Act as the strategic and operational integrator for Canada launch readiness: establish governance, workstreams, milestones, decision points, dependencies, escalation paths, and performance measures across functions. Partner closely with Senior Marketing Engagement Leads and transition launch leadership at the agreed point in the launch lifecycle, ensuring continuity of decisions, plans, and accountabilities. Performance visibility, analytics &

• AI-enabled operational insights Partner with Insights &

• Analytics to evolve the LOC commercial performance-management ecosystem, including KPI scorecards, operational health measures, execution-to-plan indicators, and management reporting. Support executive decision-making by translating data, risks, and cross-functional inputs into concise “so what / now what” narratives, options, and recommendations

- Coordinate development of business case and launch-review presentations, ensuring recommendations, risks, assumptions, and required decisions are aligned before governance forums. Leverage AI and automation responsibly to improve the speed, quality, and consistency of operational work products, ensuring appropriate human oversight and adherence to Takeda standards for privacy and compliance. Operational excellence, continuous improvement & compliance coordination Apply structured problem-solving and root-cause analysis to performance gaps, execution barriers, and recurring governance issues
- Identify opportunities to simplify processes, reduce cycle time, improve meeting effectiveness, and strengthen cross-functional ways of working through clearer standards, digital tooling, and automation. Support governance and compliance processes by coordinating documentation, approvals, follow-ups,



and implementation tracking with Compliance, Medical, Legal, and other stakeholders as appropriate. Maintain high-quality standards for planning materials, presentations, communications, decision records, and action logs, ensuring clarity, consistency, and traceability. Contribute to operational-risk identification across timelines, resourcing, dependencies, and process controls
- Head of Commercial & Marketing Operations and Canada Leadership Team Rare and Specialty Business Unit leadership Omnichannel Marketing (NGCE) Lead and CRM Sales leadership and people managers Finance, DD&T;, Compliance, Medical, Legal, Regulatory, and other launch partners Bachelor’s degree required; advanced degree (MBA/MSc) and/or relevant certification (e.g., 7–10+ years in commercial operations, business operations, commercial excellence, strategy execution, or an equivalent role within a matrixed, regulated industry; pharmaceutical or biotechnology experience preferred. ~ Demonstrated experience designing or running operating cadences, governance forums, planning cycles, and cross-functional programs. ~ Experience supporting launch readiness or other complex, milestone-driven programs involving multiple functions and senior stakeholders is strongly preferred. ~ Strong enterprise mindset with the ability to influence without authority, align senior stakeholders around shared priorities, and respectfully hold peers and leaders accountable to commitments. ~ Strong facilitation, conflict-resolution, and stakeholder-management skills
- Digital, analytics, and AI literacy sufficient to convert complex inputs into decision-ready narratives and improve operational effectiveness, while maintaining appropriate compliance and human oversight. ~ produces concise, polished materials and presents complex recommendations effectively to senior leadership. ~ This person creates clarity without creating bureaucracy, builds accountability without taking ownership away from the business, and brings together governance, insight, and cross-functional execution so leaders can make decisions and deliver on commitments.

Location: Toronto, Ontario (Head Office) Hybrid, 2 days per week minimum Travel: approximately 10% domestically and/or internationally Languages: English fluency required

- French fluency a strong asset In accordance with our accommodation policies and applicable provincial accessibility legislation, please advise us if you need accommodation in order to participate in the recruitment process. Full time #

📌 Senior Manager, Commercial Sales Operations (Toronto)
🏢 Takeda Pharmaceutical
📍 Toronto