Our mission is to Profoundly change the standard of care by creating a tomorrow where clinicians can confidently ablate tissue with precision; a tomorrow where patients have access to safe and effective treatment options, so they can quickly return to their daily lives. Changing the standard of care is part of our fabric. We are a group of energetic, problem-solvers focused on innovation, and looking to change the world. We are changing the paradigm for treating diseases such as prostate cancer by using real-time MR Imaging, thermal ultrasound and close-loop temperature feedback control, to gently ablate the diseased tissue with minimal side effects.If you share our values and want to work in a collaborative results focused culture and want to make a Profound impact in healthcare and your career, here is your chance.General Accountability:The Clinical Research Associate will be responsible for analyzing, questioning, and improving how work gets done while demonstrating strong foundational CRA capabilities, meeting business objectives through efficient, quality trial execution from startup to closeout.Duties and ResponsibilitiesExecute core clinical operations activities with attention to both detail and underlying context: site management, SIV, IMV, closeout visits, Trial Master File (TMF) maintenance, etcParticipate in review of site contracts, budgets, and ethics board submissionsBuild and maintain effective relationships with study personnelInvestigate issues independently, identify root causes, and propose solutionsEnsure study data are accurate, complete, and verifiable through source data review/verification (SDR/SDV) by on-site, remote,



or centralized monitoring activitiesAnalyze site and study data to identify inconsistencies, trends, or potential risks and develop mitigation strategiesEngage sites as a thought partner to improve protocol understanding and executionCommunicate findings, issues, and recommendations in a explicit, structured, concise, and results-generating mannerMaintain TMF documentation that is clear, logical, compliant, and inspection-readyContinuously seek opportunities to improve processes, clarity, and efficiencyEnsure that the study conduct, TMF, and adverse event reporting are compliant with the ethics board approval, Good Clinical Practice (GCP) guidelines, and all applicable local regulatory requirementsConduct training for colleagues or study team as requestedFulfill other duties as required and requested by the companyEducationBachelor's degree in biomedical sciences required.MSc (thesis-based preferred) or equivalent research experience.CertificationsSOCRA/CCRP or ACRP certification preferable/ completion of a clinical research graduate certificate.Key AttributesAbility to think critically beyond following processMinimum of 1 - 3 years of experienceStrong written communication skills that are transparent, concise, and logicalHigh level of initiative, ownership,



and work ethicsAbility to structure and present information clearlyAttention to detail combined with big-picture thinkingExperience in administering and conducting clinical trials from startup to closeoutProficiency in GCP guidelines, ethics board policies, applicable regulatory requirements, and all related processesProven ability to establish and maintain relationships with study site personnelProficiency in data management and quality managementKnowledge of adverse event reporting procedures and applicable regulatory requirementsExperience in conducting site initiation visits, monitoring visits, and close-out visits - both on-site and remotelyOutstanding interpersonal and communication skillsAbility to manage multiple tasks simultaneously, track project milestones, and ensure timely delivery of resultsStrong attention to detailStrong ability to work both independently and collaborativelyAbility to travel for site visits, monitoring visits, SIVs, and investigator interactions up to 60% of the time within Canada and United States.The expected annual salary range for this role is $60,000 - 75,000 CAD. Actual compensation will be determined based on experience, qualifications, and job-related factors. This role may also be eligible for participation in the company's benefits programs, such as a group RRSP and medical benefits paid by the employer.We strive to promote diversity and equal opportunity in the workplace and encourage applications from all qualified individuals, including those with disabilities. If selected to participate in the recruitment, selection, and/or assessment process, please inform Human Resources of the nature of any accommodation(s) that you may require.

📌 Clinical Research Associate (Mississauga)
🏢 Profound Medical
📍 Mississauga