The Vocadlo research group is seeking a Research Technician to join our team located in the Department of Molecular Biology and Biochemistry and the Department of Chemistry at Simon Fraser University.

Our interdisciplinary team comprises both biologists and chemists that focus on addressing fundamental questions related to the roles of carbohydrate processing enzymes in human health and disease. We use a range of methods from biochemistry to cell biology and leverage expertise in chemical biology to create and exploit new research tools.

The successful applicant(s) will work as part of this well-funded, supportive, and collegial team with a principal role being to assist in research efforts into the roles of enzymes genetically or pharmacologically linked to diseases of the central nervous system (CNS). Prospective projects benefit from a great depth of preliminary research and involve the use of human patient iPSC-derived cell models of monogenic and polygenic CNS diseases. The applicant(s) will be trained and guided by experts in cell biology and have access to cutting edge facilities including the fully automated Centre for High-Throughput Chemical Biology (HTCB), which supports automated cell culture and quantitative cell biology.

Applicant(s) will collaborate with a team of researchers to conduct experiments. Your hands-on experience with techniques in molecular biology and biochemistry or cell biology and stem cells will be pivotal to our success. Training to complement existing skills will be provided.

Key Responsibilities:

· Perform laboratory experiments and assays related to molecular biology.

· Execute western blot, nuclear acid isolation, qPCR, gene cloning, protein expression and purification, cell-based assay, microscope imaging, and other relevant techniques with precision.

· Cultivate and maintain various cell lines, including iPSCs and iPSC-derived lines following meticulous cell culture practices.

· Purify DNA and RNA samples to a high level to enable downstream analysis.

· Perform CRISPR-Cas9, confocal microscopy,



high-content imaging, and iPSC culture and differentiation (After receiving training).

· Contribute to the optimization of existing experimental protocols and methodologies.

· Collaborate with fellow researchers to ensure seamless project execution.

· Basic experimental design, procuring and producing specialized reagent, maintaining equipment, and an ability to analyze experimental results,

· Participate in publications by generating figures, methods sections and input.

The successful applicant(s) will be motivated and have a demonstrated ability to work both independently and within a team. The successful applicant must have at least a B.Sc. in Molecular Biology, Biochemistry, Biotechnology, or a related field. Familiarity with a range of methods in Molecular Cell Biology is important and training will be available to expand professional skills and abilities.

The successful applicant must be conscientious, have good communication skills, and demonstrate excellent initiative. Suitably qualified applicants are welcomed to submit an application that includes; (i) a cover letter describing their interest and suitability for this position, (ii) a resume that summarizes their background and experience, (iii) the names and contact information for two references. Application materials should be combined into a single PDF document and submitted via email to "Pierre-Andre Gilormini" [email protected].

Applications will be reviewed on a continuing basis and continue until the position is filled. The opportunity is open immediately and the appointment will be made initially for one year with the potential for renewal.





Salary will be based on experience and will start in a range from 42-54k per year.

Summary-

Location: Simon Fraser University, Burnaby Campus

Employment Group: Research Assistant

Job Category: Research/Technical - Non Union

Classification Title: Technician (Cell Biology and Molecular Biology)

Business Title: Technician

VP/Faculty: Faculty of Science

Department: Molecular Biology and Biochemistry, Chemistry

Salary: 42 k to 54 k depending on experience

Full/Part Time: Full-Time

Desired Start Date: ASAP

Possibility of Extension: Yes

Funding Type: Grant Funded

Available Openings: 1

Supervision Received: This position will report to the Principal Investigator and will work with a team of research associates, postdoctoral fellows, research technicians, graduate and undergraduate students.

Supervision Given: Training of junior group members in experimental methods.

Consequence of Error/Judgement: The candidate should have good judgment regarding safe and productive laboratory practices. Safety Training will be offered and is required for duties. Any neglect will cause delay in progressing with ongoing research which will have a negative impact on grant funding.

Qualifications: At least B.Sc. degree in a relevant discipline or Graduation from a technical college or institute. Must have some technical experience in molecular biology, cell biology, or a related discipline that includes familiarity with standard methods in immunoblotting. Desirable, but not essential, would be skills in stem cell culture, genome engineering, microscopy, recombinant protein expression, and recombinant protein purification.

Ability to prepare complete, concise, and understandable technical documentation. Ability to work in a team environment. Ability to resolve technical problems in an innovative manner. Demonstrated conscientiousness in research habits.

Ability to understand and apply policies, procedures, and instructions.

Pay: $42,000.00-$54,000.00 per year

Work Location: In person

📌 Research Technician in Cell Biology and Molecular Biology (Burnaby)
🏢 Simon Fraser University
📍 Burnaby