Compensation: CAD 65000 - CAD 115000 - yearlyCompany DescriptionChronological ageing is a biological process that results in accumulated cellular damage, ultimately driving the onset of metabolic disfunction. We aim to develop recent therapeutic approaches to these ageing-associated diseases, by targeting metabolism in cancer stem cells (CSCs) and senescent fibroblasts. More specifically, we will screen a series of chemical libraries containing FDA-approved drugs, natural products, and novel chemical entities, to identify compounds that can effectively age-associated metabolic features. Through this screening and validation approach, we will identify compounds that preferentially kill CSCs and senescent fibroblasts, using established cell lines.This position will involve the screening and discovery of drugs that target the metabolic phenotype of senescent cells and cancer stem cells, across multiple cancer types.Job DescriptionThe purpose of this role is to support Lunella Biotech's mission in the discovery of anti-ageing and anti-cancer therapeutics. In more detail, you will work as part of a team of scientists, and will be responsible for the co-planning and execution of many experimental aspects of the project. This position will involve the identification and phenotypic validation of drugs that target senescent cells and cancer stem cells. The project will require the use of immunohistochemistry,



immunocytochemistry and flow cytometry applied to relevant samples.ResponsibilitiesTo perform experiments in the laboratory to test hypotheses regarding ageing and cancerTo plan and execute the experiments related to the phenotypic validation of identified drugs targeting CSCs and senescent cells.To apply complex research techniques for the phenotypic validation of drug hits using immunohistochemistry, immunofluorescence and flow cytometry of relevant samples.Take overall responsibility for several experimental components of the project.To maintain accurate records of data and analysis performed of specific experiments for a given project, conducts literature searches, and maintains an up-to-date knowledge of all current experimental methods through professional reading.To demonstrate a willingness to adapt and develop new skills.To write up draft reports for manuscript publication and patent evaluationTo present data as required, during lab meetings and conferencesTo collaborate with members within and outside of the laboratoryTo comply with Health and Safety regulationsTo promote equality and diversity and sustain an inclusive and supportive work environmentThis role detail is a guide to the work you will initially be required to undertake.



It may be changed from time to time to meet changing circumstancesQualificationsEducationCompleted Master's or PhD in related biological/pharmaceutical sciencesPublication record in peer-reviewed journalsExperience in flow cytometry/FACS analysisConsiderable experience of cell culture techniquesExperience in fluorescent microscopyExperience and a track record in working with and developing a variety of techniquesExperience in recording, analyzing and interpreting dataExperience in assays measuring metabolic parameters of cellular modelsExperience in the co-culture of multiple cell typesExperience in proteomicsExperience in the generation of stable cell lines using transfection methodsProven ability to maintain high experimental reproducibility and reliability to ensure consistent and valid resultsAbility to work independently within an agreed frameworkExcellent communication skills on paper and verbally, including good IT skillsAbility to work as part of a teamProven ability to follow directionsAbility and willingness to learn new analytical methods and skillsGood organizational skillsAdditional informationAs an equal opportunity employer, Lunella Biotech Inc. is committed to achieving a skilled and diversified workforce that reflects the diversity of the Canadian population. We encourage applications from women, visible minorities, people with disabilities and Aboriginal people.Additional InformationAs an equal opportunity employer, Lunella Biotech Inc. is committed to achieving a skilled and diversified workforce that reflects the diversity of the Canadian population. We encourage applications from women, visible minorities, people with disabilities and Aboriginal people.

📌 Biomedical Scientist (Riviere-des-Prairies—Pointe-aux-Trembles)
🏢 Canadian Bank Note Company
📍 Riviere-des-Prairies—Pointe-aux-Trembles