We are seeking a highly motivated Postdoctoral Fellow to join an exciting interdisciplinary project investigating how aging of the haematopoietic microenvironment influences stem cell health and the earliest events in leukaemia development. The successful candidate will explore how extracellular vesicles (EVs) from the blood and bone microenvironment regulate haematopoietic stem/progenitor cell function during aging, with a particular focus on the stress-response regulators p53 and HSF1. Using primary human HSPCs, functional and molecular assays, single-cell approaches and xenograft mouse models, the project will determine how age-associated EV signalling affects stem cell quiescence, proliferation and long-term engraftment. This position offers an opportunity to work at the interface of stem cell biology, aging, extracellular vesicles and cancer, uncovering mechanisms that may explain how an aging bone microenvironment creates conditions that favour malignant transformation.

https://abrahamstemcells.com/

Role Description The Postdoctoral Researcher will lead an independent research project and contribute to collaborative projects within the group. Responsibilities include designing and conducting experiments, collecting and analyzing data, preparing manuscripts for publication, and assisting in the development of grant proposals.

We offer a competitive salary plus advantages





Work week is 37.5 hours/week

Qualifications

- PhD degree in disciplines related to biomedical research and extracellular vesicles and or leukaemia.
- Demonstrated scientific productivity and a minimum of 2 peer-reviewed publications in international journals.
- Excellent laboratory and research skills.
- Expertise in microscopy, basic biochemistry and cell biology techniques.
- Effective teaching skills, including mentoring students and presenting scientific concepts.
- Proven ability to multi-task in a deadline oriented environment with minimal supervision
- Effective oral and written communication, analytical, and interpersonal skills
- Excellent organizational skill and ability to learn new skills quickly
- Ability to work independently and within a team workplace.
- Accuracy and attention to detail required
- Candidates should demonstrate the ability to work in a highly interdisciplinary workplace.

Preferred Start Date: January 2027

To Apply:

Forward your CV, a cover letter that outlines your career objectives and why you are a good fit for the project, and contact information for three references to:

Dr Sheela Abraham [email protected]

Closing date: Position open until filled

We thank all applicants for their interest; however, only those individuals selected for an interview will be contacted.

📌 Post doctorate researcher (Kingston)
🏢 Queen's University
📍 Kingston