15 Sep
|
Canadian Bank Note Company
|
Ottawa
15 Sep
Canadian Bank Note Company
Ottawa
Compensation: CAD 65000 - CAD 115000 - yearly Chronological ageing is a biological process that results in accumulated cellular damage, ultimately driving the onset of metabolic disfunction. We aim to develop new therapeutic approaches to these ageing-associated diseases, by targeting metabolism in cancer stem cells (CSCs) and senescent fibroblasts. More specifically, we will screen a series of chemical libraries containing FDA-approved drugs, natural products, and novel chemical entities, to identify compounds that can effectively age-associated metabolic features.
Through this screening and validation approach, we will identify compounds that preferentially kill CSCs and senescent fibroblasts, using established cell lines. The purpose of this role is to support Lunella Biotech’s mission in the discovery of anti-ageing and anti-cancer therapeutics. In more detail, you will work as part of a team of scientists, and will be responsible for the co-planning and execution of many experimental aspects of the project.
The project will require the use of immunohistochemistry, immunocytochemistry and flow cytometry applied to relevant samples. To perform experiments in the laboratory to test hypotheses regarding ageing and cancer To plan and execute the experiments related to the phenotypic validation of identified drugs targeting CSCs and senescent cells. To apply complex research techniques for the phenotypic validation of drug hits using immunohistochemistry, immunofluorescence and flow cytometry of relevant samples.
Take overall responsibility for several experimental components of the project. To maintain accurate records of data and analysis performed of specific experiments for a given project, conducts literature searches, and maintains an up-to-date knowledge of all current experimental methods through professional reading. To write up draft reports for manuscript publication and patent evaluation To present data as required, during lab meetings and conferences To collaborate with members within and outside of the laboratory To promote equality and diversity and sustain an inclusive and supportive work setting Completed Master’s or PhD in related biological/pharmaceutical sciences Experience in flow cytometry/FACS analysis Considerable experience of cell culture techniques Experience and a track record in working with and developing a variety of techniques Experience in recording, analyzing and interpreting data As an equal opportunity employer, Lunella Biotech Inc. is committed to achieving a skilled and diversified workforce that reflects the diversity of the Canadian population.
We encourage applications from women, visible minorities, people with disabilities and Aboriginal people. As an equal opportunity employer, Lunella Biotech Inc. is committed to achieving a skilled and diversified workforce that reflects the diversity of the Canadian population. We encourage applications from women, visible minorities, people with disabilities and Aboriginal people. #
📌 Haematology & Blood Transfusion - Biomedical Scientist (Ottawa)
🏢 Canadian Bank Note Company
📍 Ottawa