Academic Job Category Faculty Non Bargaining Job Title Postdoctoral Research Fellow – Human Neuroimmunology, Brain Organoids and Multi-omics Department MS Research Network | Department of Medicine | Faculty of Medicine (Jan Lunemann) Posting End Date September 26, 2026 Note: Applications will be accepted until 11:59 PM on the Posting End Date. This is a 2-year term appointment with the possibility of extension The expected pay range for this position is CAD $65,000–75,000 per annum plus benefits. The Department of Medicine, Faculty of Medicine is committed to offering equitable and competitive salaries, commensurate with the qualifications and experience of the candidate.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.

Job Summary The Laboratory of Professor Jan D. Lünemann, UBC Chair in Multiple Sclerosis and Autoimmune Neurology Research, invites applications for a highly motivated and intellectually curious Postdoctoral Fellow to join an interdisciplinary research program at the Djavad Mowafaghian Centre for Brain Health (DMCBH), one of Canada's leading neuroscience research centres. The project combines human induced pluripotent stem cell (hiPSC) technology, brain organoids, genome engineering, advanced imaging, systems immunology, and high‑throughput multi‑omics to investigate neuroimmune interactions and identify novel therapeutic targets.

The successful candidate will join a rapidly expanding international research program dedicated to uncovering the mechanisms of immune‑mediated diseases of the nervous system through human discovery science. Embedded within an extensive interdisciplinary network of experts in neuroimmunology, stem cell biology, biomedical engineering, computational biology, artificial intelligence, and precision medicine across UBC, they will have access to cutting‑edge research infrastructure, including human stem cell and organoid platforms, genome engineering technologies, advanced microscopy, spectral flow cytometry, single‑cell and spatial genomics, proteomics and biomarker laboratories, and high‑performance computational resources. The laboratory is deeply committed to excellent mentorship and fostering the professional development of early‑career researchers through extensive national and international collaborations.

The Postdoctoral Research

Fellow will report directly to Professor Lünemann and collaborate closely with investigators across the Faculty of Medicine, DMCBH, the School of Biomedical Engineering, the Life Sciences Institute, and national and international collaborators. Professor Lünemann is the inaugural UBC Chair in Multiple Sclerosis and Autoimmune Neurology Research and Director of the UBC MS & Neuromyelitis Optica Programme. His laboratory combines human discovery science with advanced experimental technologies to understand disease mechanisms and develop precision therapeutics for autoimmune neurological diseases.

Design and lead innovative research projects investigating mechanisms of neuroinflammation and neurodegeneration.



Apply advanced microscopy techniques including confocal microscopy, live‑cell imaging, high‑content imaging, and three‑dimensional image analysis. Perform and integrate high‑dimensional molecular analyses, including single‑cell RNA sequencing, spatial transcriptomics, proteomics, immune repertoire sequencing, and other multi‑omics technologies.

Collaborate with computational scientists to analyse large‑scale datasets using state‑of‑the‑art bioinformatics and artificial intelligence approaches. Prepare manuscripts for publication in leading international journals. Present research findings at national and international scientific meetings.

Contribute to grant applications and collaborative research initiatives. Mentor graduate students, undergraduate trainees, and research assistants within the laboratory. Contribute to establishing a cooperative, inclusive, and scientifically stimulating research environment.

Supervision Received The candidate will work under the direct supervision of Professor Jan D. Lünemann while maintaining a high degree of scientific independence. The candidate will be expected to develop independent research directions aligned with the laboratory's overall research strategy and contribute intellectually to collaborative projects.

Supervision Given The candidate will provide scientific mentorship to graduate students, undergraduate researchers, visiting trainees, and research assistants, including technical training and day‑to‑day guidance within research projects. PhD (or equivalent) in neuroscience, immunology, stem cell biology, molecular biology, genetics, biomedical engineering, or a closely related discipline. Demonstrated research excellence through peer‑reviewed publications.

Demonstrated ability to work independently and effectively in an interdisciplinary and collaborative research environment with excellent organizational and communication skills. Commitment to enhancing awareness, knowledge and skills related to equity, diversity, and inclusion. Scientific curiosity, creativity and a strong commitment to scientific rigor, reproducibility, and open science.

Stem Cell

Biology and Disease Modelling Experience Strong background in cellular and molecular immunology, including human B‑cell and T‑cell biology, antibody responses, and humoral immunity, immune activation, immune regulation, and adaptive immune responses.

Experience with complement biology or antibody‑mediated neurological diseases is considered an asset.

Immunological Techniques

Human immune cell isolation and culture.

Genetic Engineering

Experience with CRISPR/Cas9 genome editing, CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa), generation of genetically engineered hiPSC lines, and viral vector technologies.

Experience with ocnfocal microscopy, high‑content imaging,live‑cell imaging. Three‑dimensional image reconstruction and quantitative image analysis using Fiji/ImageJ,



CellProfiler, Imaris, or related software. Bioinformatics and Data Analysis Experience analysing high‑dimensional biological datasets. Proficiency in R for statistical analysis, visualization, and reproducible data analysis.

Experience with packages such as Seurat, Bioconductor, tidyverse, SingleCellExperiment, or related software.

Experience with Python and machine learning approaches is considered an asset. The University of British Columbia is committed to creating and maintaining an inclusive, equitable, and diverse workplace. Within this hiring process we are committed to creating an inclusive and equitable process for all candidates (including but not limited to people with disabilities).

Confidential accommodations are available on request. If you have any questions regarding accommodations or accessibility during the recruitment and hiring process or for more information and support, please visit UBC’s Centre for Workplace Accessibility website at or contact the Centre at workplace.The University of British Columbia is a global centre for research and teaching, consistently ranked among the top 20 public universities in the world.

Our Vision: To Transform Health for Everyone Ranked among the world’s top medical schools with the fifth‑largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine.

Across British

Columbia, more than 12,000 faculty and staff are training the next generation of doctors and health‑care professionals, making remarkable discoveries, and helping to create the pathways to better health for our communities at home and around the world. The Faculty of Medicine —comprised of approximately 2,600 administrative support, technical/research and management and professional staff, as well approximately 620 full‑time academic and over 14,000 clinical faculty members—is composed of 19 academic basic science and/or clinical departments, 3 schools, and 26 research centres and institutes. Together with its University and Health Authority partners, the Faculty of Medicine delivers innovative programs and conducts research in the areas of health and life sciences.

Faculty, staff and trainees are located at university campuses, clinical academic campuses in hospital settings and other regionally based centres across the province. UBC - One of the World’s Leading Universities As one of the world’s leading universities, the University of British Columbia creates an exceptional learning environment that fosters global citizenship, advances a civil and sustainable society, and supports outstanding research to serve the people of British Columbia, Canada and the world. UBC hires on the basis of merit and is committed to employment equity.

All qualified persons are encouraged to apply. Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.

Human Rights

Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, and/or Indigenous person. however Canadians and permanent residents will be given priority.

📌 Postdoctoral Research Fellow Full-time (Vancouver)
🏢 The University of British Columbia
📍 Vancouver