Our mission is to Profoundly change the standard of care by creating a tomorrow where clinicians can confidently ablate tissue with precision; Changing the standard of care is part of our fabric. We are a group of energetic, problem-solvers focused on innovation, and looking to change the world. We are changing the paradigm for treating diseases such as prostate cancer by using real-time MR Imaging, thermal ultrasound and close-loop temperature feedback control, to gently ablate the diseased tissue with minimal side effects.

If you share our values and want to work in a collaborative results focused culture and want to make a Profound impact in healthcare and your career, here is your chance.

The Clinical Research

Associate will be responsible for analyzing, questioning, and improving how work gets done while demonstrating strong foundational CRA capabilities, meeting business objectives through efficient, quality trial execution from startup to closeout. Execute core clinical operations activities with attention to both detail and underlying context: site management, SIV, IMV, closeout visits, Trial Master File (TMF) maintenance, etc Participate in review of site contracts, budgets, and ethics board submissions Ensure study data are accurate, complete, and verifiable through source data review/verification (SDR/SDV) by on-site, remote, or centralized monitoring activities Analyze site and study data to identify inconsistencies, trends, or potential risks and develop mitigation strategies Engage sites as a thought partner to improve protocol understanding and execution Maintain TMF documentation that is clear, logical, compliant, and inspection-ready Ensure that the study conduct, TMF,



and adverse event reporting are compliant with the ethics board approval, Good Clinical Practice (GCP) guidelines, and all applicable local regulatory requirements Conduct training for colleagues or study team as requested Bachelor’s degree in biomedical sciences required. MSc (thesis-based preferred) or equivalent research experience.

SOCRA/CCRP or ACRP certification preferable/ completion of a clinical research graduate certificate.

Experience in administering and conducting clinical trials from startup to closeout Proficiency in GCP guidelines, ethics board policies, applicable regulatory requirements, and all related processes Proven ability to establish and maintain relationships with study site personnel Proficiency in data management and quality management Knowledge of adverse event reporting procedures and applicable regulatory requirements Experience in conducting site initiation visits, monitoring visits, and close-out visits - both in office and remotely Ability to manage multiple tasks simultaneously, track project milestones, and ensure timely delivery of results Ability to travel for site visits, monitoring visits, SIVs, and investigator interactions up to 60% of the time within Canada and United States. We thank you for your interest in Profound Medical. The expected annual salary range for this role is $60,000 - 75,000 CAD.

This role may also be eligible for participation in the company’s benefits programs, such as a group RRSP and medical benefits paid by the employer. We strive to promote diversity and equal opportunity in the workplace and encourage applications from all qualified individuals, including those with disabilities.

📌 Clinical Data Research Associate (Mississauga)
🏢 PulseMedica
📍 Mississauga