Postdoctoral Research Scientist - Neuronal cell biologist in Parkinson’s At the Department of Physiology Anatomy & Genetics (DPAG) we undertake discovery science where we reassemble physiological processes at the molecular, cellular, tissue and systems level of organisation. In so doing we provide a bridge to translational medicine, and interface between physical and life sciences. We are committed not only to innovative research and the highest standard of teaching, but also to creating an inclusive and supportive working environment.

Overview of the role: We are seeking a Post-Doctoral neuronal cell biologist to join the Wade-Martins Laboratory at the Kavli Institute of Nanoscience Discovery within DPAG. The ideal candidate will be a neuronal cell biologist with experience working in neuronal models of neurodegeneration, ideally in human stem cell-derived models, and a good knowledge of Parkinson’s disease. This is an exciting collaborative opportunity to contribute to the development of a novel therapeutic approach for Parkinson’s, a major age-related neurodegenerative disease, at the interface between academic research and target and drug discovery using state-of-the art human stem cell-derived neuronal models In this role, you will be responsible for differentiation of iPSC-dopamine neurons from Parkinson’s patients and controls and applying cellular and molecular techniques to probe endolysosomal and mitochondrial biology, including metabolic and lipidomic profiling, to validate a novel therapeutic target.





This post is available immediately for two years.

Key responsibilities

- Lead on the differentiation of iPSC-dopamine neurons from Parkinson’s patients and controls and apply cellular and molecular techniques to probe endolysosomal and mitochondrial biology - Lead on analysis of the phenotypic effect of pharmacological inhibitors on cell biology phenotypes in cellular models of Parkinson’s - Lead on metabolic and lipidomic profiling in iPSC-dopamine neurons to look at relevant biological pathways - Manage own academic research and administrative activities. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines - Adapt existing and develop new scientific techniques and experimental protocols - Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate - Contribute ideas for current research projects - Develop ideas for generating research income, and present detailed research proposals to senior researchers - Collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters - Use specialist scientific equipment in a laboratory environment - Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques - Represent the research group at external meetings/seminars, either with other members of the group or alone

📌 Postdoctoral Research Scientist - Neuronal cell biologist in Parkinson’s (Halifax Regional Municipality)
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