About Us:

QurCan Therapeutics is a forward-thinking biotech company harnessing next-generation nanoparticle technology for the advancement of genetic and biological therapeutics. We are excited to welcome motivated and innovative minds to our R&D; site in Toronto. We're currently seeking a highly motivated Associate scientist with a MSc/PhD in neuroscience & molecular biology to be part of our dynamic product development team.

Position Overview:

As a Molecular Biology Research Associate/Associate Neuroscientist, you will contribute your expertise to our cutting-edge research in nucleic acid assay development. Collaborating within a cross-disciplinary team of scientists, you will tackle complex challenges in designing and conducting molecular biology, cell-based, and animal studies to evaluate therapeutic efficacy, safety, biodistribution, and mechanisms of action.

Tasks and Responsibilities

- Design, plan, and execute in vitro and in vivo studies supporting the development of RNA therapeutics
- Evaluate novel siRNA and mRNA-based formulations using fluorescent and immunology-based assays in vitro and ex vivo
- Perform molecular and cellular biology assays to assess changes in gene and protein expression
- Conduct techniques such as quantitative PCR, RT-qPCR, Western blotting, ELISA, immunocytochemistry, and related analytical assays.
- Implementation and refinement of protocols.

- Conducting RNA/DNA sequencing
- Conducting cell-based assays, which involve the cultivation and seeding of cell lines and primary cells, as well as executing transfection experiments
- Maintenance of meticulous lab records, regular data analysis, and contribution to shared records.
- Effective management of critical reagent inventories such as cells, media, and cytokines.
- Plan and conduct preclinical animal studies to evaluate therapeutic efficacy, safety, tolerability, biodistribution, and pharmacodynamic responses.

-Able to create high-throughput experimental designs,



address technical challenges, analyze data, and communicate findings to teams effectively

Requirements:

- M.S./Ph.D. degree neuroscience and molecular biology
- Demonstrated experience evaluating gene and protein expression using relevant molecular and biochemical techniques.
- Having years of experience in siRNA and mRNA modifications and in-vitro studies
- Strong experience in cell culture, cell treatments, gene expression and silencing assays in mammalian cells lines.
- Experience processing tissues and assessing molecular, cellular, or histological changes.
- Strong scientific writing, data interpretation, presentation, and communication skills.

Preferred:

- MSc/PhD, recently graduated from a Canadian academic institution, with high enthusiasm in new scientific discoveries and trends in the biotechnology field.

Why Join Us:

- Be at the forefront of pioneering research in the biotech industry.
- Collaborate with a diverse team of experts.
- Opportunity for professional growth and development.
- Contribute to shaping the future of genetic and biological therapeutics.

Application Process: If you are enthusiastic about being part of our cutting-edge journey, please apply by submitting your resume and cover letter through our online application portal. We appreciate your interest in QurCan Therapeutics; only shortlisted candidates will be contacted.

Job Type: Full-time

Pay: From $70,000.00 per year

Application question(s)

- Have you done gene expression/silencing experiments in mammalian cell lines?
- Do you have a PhD degree in neuroscience, Cellular and Molecular Biology, genetics, or relevant fields?
- Do you have in-vivo work experience?
- Are you graduated from a Canadian institution?
- How many years have passed since your graduation?
- Do you have more than 3 years of cell culture experience using human/murine cells lines?

Education:
- Master's Degree (required)

Experience:
- Laboratory: 4 years (preferred)

Work Location: In person

📌 Associate Scientist- Neuroscientist (Toronto)
🏢 QurCan Therapeutics
📍 Toronto