Principal Clinical Scientist (AI Training) About The Role What if your years of clinical trial expertise could directly shape how AI understands, evaluates, and reasons about medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring that the clinical data powering next-generation AI systems meets the same standards expected in real-world regulatory submissions. This is a fully remote, adaptable contract role designed for experienced clinical scientists who want to work at the intersection of medicine and frontier AI.

Organization: Alignerr

Type: Hourly Contract

Location: Remote

Commitment: 10–40 hours/week What You'll Do Design and review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training

Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory standards

Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations

Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, outcomes, and evidence





Work independently and asynchronously — fully on your own schedule Who You Are Senior-level experience designing clinical trial protocols intended for regulatory submission

Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent

Strong background in clinical research methodology, biostatistics, or translational science

Naturally rigorous and detail-oriented — you hold AI outputs to the same standards you'd apply to a real submission

Clear and confident communicator who can translate complex clinical concepts into actionable feedback Nice to Have Prior experience with data annotation, data quality review, or AI evaluation systems

Background in pharmacovigilance, medical affairs, or clinical operations

Familiarity with AI tools or content evaluation workflows

Experience working across multiple therapeutic areas or regulatory jurisdictions Why Join Us Work directly on frontier AI systems that are reshaping clinical and biomedical research

Influence how AI understands, evaluates, and applies real-world clinical evidence

Fully remote and flexible — work when and where it suits you

Freelance autonomy with the structure of meaningful, expert-level work

Collaborate with world-leading AI research teams and labs on high-impact projects

Potential for ongoing work and contract extension as new projects launch

📌 Principal Clinical Scientist (Canada)
🏢 Alignerr
📍 Canada