Domain Expert - Pharmacy (UpToDate Lexidrug)
To qualify you must use UpToDate Lexidrug (or Lexicomp) regularly - weekly or more - as a working part of your job, with 2+ years of qualified pharmacy experience.

Lexidrug knowledge we require

Core (required of all candidates)

Knows how to work a full medication-list interaction check to completion - not just confirm a single named pair, but judge severity ratings and mechanism of interaction across the whole list

Knows how to weigh contraindications, boxed warnings, and warnings/precautions against a specific patient's situation, not just check whether a flag exists

Knows how to distinguish "not contraindicated" from "appropriate for this patient" - and where in the monograph that second judgment actually gets made

Knows how to reconcile a Special Alert against monograph content when they conflict - recognizes alerts generally take precedence until reconciled

Knows how to apply renal/hepatic dose-adjustment logic and calculators correctly given current patient data (labs, weight), not just plug in numbers

Specialized depth (strong working knowledge in at least 2-3 of the following)

Trissel's IV Compatibility (physical/chemical incompatibility vs. physiological interaction - knows these are distinct problems, not one nested in the other)

Pediatric/weight-based dosing

Beers Criteria / geriatric-specific precautions

Pregnancy and lactation risk categories

REMS and prescribing/access restrictions (controlled substance scheduling, restricted distribution programs)

Therapeutic class comparison for alternatives (allergy, shortage, formulary substitution)

Drug I.D.



and patient education / multi-language handouts

What you'll do

Confirm an interaction, dosing, or contraindication finding holds up against the patient's full medication list and chart - not just the two drugs named in the question

Catch missed interactions, stale patient data (outdated labs/weight) driving a wrong dose, and monograph guidance superseded by a newer Special Alert

Judge completeness: is the full clinical picture (all active meds, current labs, comorbidities) accounted for, or was the question scoped too narrowly

Distinguish "permitted" from "appropriate" - flag when a drug clears interaction/contraindication checks but is still a poor choice for this specific patient

Verify that a correct clinical conclusion is actually carried through - order updated, prescriber notified, chart/note documented - not just identified and left there

Requirements

Frequent Lexidrug (or Lexicomp) use - weekly or more - in your current or recent role

2+ years of professional pharmacy experience, inpatient/hospital setting strongly preferred

Reflexive use of Interactions, Trissel's, and monograph sections; can spot a missed interaction, a stale dose calculation, or superseded guidance on sight

PharmD and active pharmacy license, or equivalent verification-heavy clinical experience

Strong working knowledge in at least 2-3 specialized areas above, tied to your practice setting (e.g., ICU, oncology, pediatrics, geriatrics)

Comfort judging whether a correct clinical finding was properly followed through into the chart, order, and care-team communication

Prior data annotation, labeling, or AI evaluation experience is a plus

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📌 Pharmacy Expert - Lexidrug Specialist (Ontario)
🏢 Obsidian
📍 Ontario