12 Aug
|
Polymorphic Biosciences
|
Vancouver
12 Aug
Polymorphic Biosciences
Vancouver
About UsPolymorphic Biosciences is a privately funded research incubator based in Vancouver, BC that explores novel applications of lipid nanoparticle technology. Our projects range from early-stage exploratory research to applied development for commercial applications.Position OverviewAs a Process Development Scientist, you will be responsible for generating the experimental data that drives our LNP manufacturing platform. This is a bench-heavy, independent role requiring hands-on expertise in lipid nanoparticle formulation and tangential flow filtration. We are a small team building something new, and we need someone who brings both rigour and adaptability to the role.Key ResponsibilitiesServe as the technical lead for LNP formulation and TFF process development, owning the experimental program from study design through to data analysis and reportingEstablish and maintain the analytical characterization workflow for LNP quality attributes (particle size, PDI, encapsulation efficiency, yield)Build the process knowledge base — defining critical process parameters, operating ranges, and reproducibility boundariesDevelop documentation and workflows to a standard that supports future scale-up and technology transfer into a cGMP environmentCommunicate findings clearly to both internal stakeholders and external partners through presentations, technical reports,
and informal updatesContribute to the broader R&D program as priorities evolveKnowledge and QualificationsRequiredMSc or PhD in chemical engineering, pharmaceutical sciences, bioengineering, or a related field, with 3+ years of relevant industry experienceHands-on experience in LNP formulation and tangential flow filtrationAdvanced technical knowledge in process development and Quality by Design (QbD) principlesStrong experimental design skills with a systematic approach to process characterizationFamiliarity with cGMP concepts and regulatory considerations in the biotech/pharmaceutical industryExcellent written and verbal communication skills, with the ability to present technical findings to diverse audiencesStrong critical thinking, attention to detail, and the ability to work independently in a developing environmentPreferredDirect experience working in or supporting a cGMP manufacturing environmentFamiliarity with RNA-based therapeutics (mRNA, siRNA)What We OfferSalary range: $70k - $100k per annumComprehensive medical and dental coverage after 3 monthsFlexible working hoursOpportunities for skilled growth and developmentCollaborative and innovative research environmentContribution to cutting-edge therapeutic development
📌 Process Development Scientist - $70,000 - $100,000 A Year (Vancouver)
🏢 Polymorphic Biosciences
📍 Vancouver