Polymorphic Biosciences is a privately funded research incubator based in Vancouver, BC that explores novel applications of lipid nanoparticle technology. Our projects range from early-stage exploratory research to applied development for commercial applications.

Position Overview

As a Process Development Scientist , you will be responsible for generating the experimental data that drives our LNP manufacturing platform. This is a bench-heavy, independent role requiring hands‑on expertise in lipid nanoparticle formulation and tangential flow filtration. We are a small team building something new, and we need someone who brings both rigour and adaptability to the role.

Key Responsibilities

- Serve as the technical lead for LNP formulation and TFF process development, owning the experimental program from study design through to data analysis and reporting
- Establish and maintain the analytical characterization workflow for LNP quality attributes (particle size, PDI, encapsulation efficiency, yield)
- Build the process knowledge base — defining critical process parameters, operating ranges, and reproducibility boundaries
- Develop documentation and workflows to a standard that supports future scale-up and technology transfer into a cGMP environment
- Communicate findings clearly to both internal stakeholders and external partners through presentations, technical reports, and informal updates




- Contribute to the broader R&D; program as priorities evolve

Knowledge and Qualifications

Required

- MSc or PhD in chemical engineering, pharmaceutical sciences, bioengineering, or a related field, with 3+ years of relevant industry experience
- Hands‑on experience in LNP formulation and tangential flow filtration
- Advanced technical knowledge in process development and Quality by Design (QbD) principles
- Strong experimental design skills with a systematic approach to process characterization
- Familiarity with cGMP concepts and regulatory considerations in the biotech/pharmaceutical industry
- Excellent written and verbal communication skills, with the ability to present technical findings to diverse audiences
- Strong critical thinking, attention to detail, and the ability to work independently in a developing environment

Preferred

- Direct experience working in or supporting a cGMP manufacturing environment
- Familiarity with RNA-based therapeutics (mRNA, siRNA)

What We Offer

- Salary range: $70k - $100k per annum
- Comprehensive medical and dental coverage after 3 months
- Opportunities for professional growth and development
- Collaborative and cutting-edge research environment
- Contribution to cutting‑edge therapeutic development

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📌 Process Development Scientist (Vancouver)
🏢 Polymorphic Biosciences
📍 Vancouver