Sitero is an emerging leader in Clinical services and software solutions for the life sciences industry. We have experience and expertise in a diverse range of therapeutic areas and focus on innovative, technology-enabled solutions that allow our clients to focus on their core strengths. For early phase studies through Phase III clinical trials, our experienced team delivers high-touch services and technology to ensure the safety of all stakeholders across the clinical research community with an emphasis on ethics, compliance, and innovation.Sitero is looking for a skilled Senior Software Engineer to primarily use Python to design, build, and maintain enterprise-grade features across our Life Sciences SaaS platform. You will work across the full technology stack — from crafting clean, responsive React frontends to building robust Python microservices — in a regulated environment that demands high code quality, security, and reliability.As part of our Engineering team, you will collaborate closely with Product Management, QA, DevOps, and Clinical domain experts to deliver compliant, scalable software that supports clinical trials, pharmacovigilance, and patient safety workflows globally.Job Title: Senior Software EngineerLocation: Mississauga, Ontario (Hybrid). 3x per week in office, 2x per week remoteFunction: EngineeringESSENTIAL DUTIES AND RESPONSIBILITIESFull Stack DevelopmentDesign and develop full-stack features using Python/FastAPI or Django (backend) and React/TypeScript (frontend)Build and maintain RESTful APIs and GraphQL endpoints consumed by internal and external systemsDevelop reusable,



maintainable UI components and integrate them with backend servicesParticipate in architecture reviews and contribute to technical design decisionsBackend EngineeringDevelop microservices following domain-driven design patterns and 12-factor app principlesImplement secure authentication and authorization using OAuth 2.0, OIDC, and Python security librariesOptimize SQL/NoSQL queries, manage database migrations (Alembic), and design effective data modelsIntegrate with third-party APIs, HL7/FHIR standards, and clinical data systems where applicableQuality & ComplianceWrite comprehensive unit, integration, and end-to-end tests (pytest, React Testing Library, Playwright/Cypress)Adhere to 21 CFR Part 11, HIPAA, and GxP standards in all development activitiesSupport IQ/OQ/PQ validation activities and maintain traceability between requirements and codeParticipate in code reviews, enforce coding standards, and contribute to static analysis (SonarQube, Ruff/Black)Collaboration & DeliveryWork in Agile/Scrum sprints; contribute to sprint planning, grooming, and retrospectivesPartner with QA on test planning, defect triage, and release readinessDocument technical designs, API specifications (OpenAPI/Swagger), and runbooksMentor junior developers and support onboarding of new team membersEDUCATION AND EXPERIENCE REQUIREDBachelor's or master's degree in computer science, Engineering, or a related field5-8 years of professional software development experienceStrong proficiency in Python 3.10+ and backend frameworks such as FastAPI or Django REST FrameworkSolid frontend experience with React.Js, TypeScript,



and modern CSS (SCSS/Tailwind)Hands-on experience with relational databases (PostgreSQL or MySQL) and query optimizationFamiliarity with containerization (Docker) and orchestration (Kubernetes)Experience with cloud platforms — AWS or Azure — and CI/CD pipeline managementStrong understanding of RESTful API design, versioning, and documentation practicesWorking knowledge of Agile methodologies and tools like JIRAPreferred QualificationsExperience in Life Sciences, Healthcare IT, or regulated software environments (GxP/21 CFR Part 11)Exposure to clinical data standards: CDISC, HL7 FHIR, or EDC/CTMS platformsKnowledge of event-driven architecture using Kafka or RabbitMQAWS Certified Developer or equivalent cloud certificationFamiliarity with Python data science ecosystem (pandas, NumPy) or ML integrationsExperience with AI/ML integrations or LLM-powered features in enterprise applicationsContributions to open-source projects or published technical contentCOMPENSATION & BENEFITSSalary range of $120,000-150,000 CADSitero proudly offers an impressive compensation package and benefits through Canada Life, including a competitive salary, paid time off, and healthcare and retirement benefits.EMPLOYMENT TYPEFull Time, PermanentCOMMITMENTSStandard Hours 40 hours per week, one hour lunch, Monday - Friday.Additional hours as needed.3x per week in office2x per week remote from homeDISCLAIMERSitero is an equal opportunity employer and welcomes all job applicants. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. #J-18808-Ljbffr

📌 Senior Software Engineer (Markham)
🏢 Sitero
📍 Markham