Principal Clinical Scientist (AI Training) About The Role What if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to the frontier of AI development — ensuring the clinical knowledge embedded in next-generation AI systems meets the highest standards of scientific and regulatory integrity. This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work on their own schedule.

No AI background required — your deep domain expertise is what matters.

Organization: Alignerr

Type: Hourly Contract

Location: Remote

Commitment: 10–40 hours/week What You'll Do Design and critically review clinical trial protocols used to generate high-quality, regulator-ready AI training datasets

Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance

Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations

Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes





Help establish quality standards for clinical evidence used in cutting-edge AI research workflows Who You Are Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission

Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)

Strong grounding in clinical research methodology, biostatistics, or translational science

Naturally rigorous and detail-oriented — you hold clinical evidence to the highest standards

Comfortable working independently and asynchronously in a remote workplace Nice to Have Prior experience with data annotation, data quality review, or evaluation frameworks

Background in clinical pharmacology, oncology, rare disease, or other specialized therapeutic areas

Familiarity with AI tools or emerging applications of machine learning in clinical research Why Join Us Work directly on frontier AI systems shaping the future of clinical and biomedical research

Influence how AI understands, evaluates, and communicates real-world clinical evidence

Fully remote and flexible — work when and where it suits you

Freelance autonomy with the structure of meaningful, expert-level work

Collaborate with world-leading AI research teams and labs

Potential for ongoing work and contract extension as new projects launch

📌 Principal Clinical Scientist (Montreal)
🏢 Alignerr
📍 Montreal