Job Responsibility Design and developtoxicology-enabling formulationsforin vivo preclinical studies(rodent and non-rodent), including: solutions, suspensions, emulsions, and lipid-based formulations.

Select formulation approaches based onAPI physicochemical properties, exposure targets, and route of administration.

Design and execute excipient compatibility studies, including lipid-API interactions.

Assess chemical and physical stability undershort-term and accelerated conditionsappropriate for tox studies.

Design and preform high throughput screening, solubility measurements and characterization.

Characterize the generated samples using X-ray Powder Diffraction (XRPD), Differential Scanning Calorimetry (DSC), Thermal Gravimetry Analysis (TGA), Liquid Nuclear Magnetic Resonance (NMR), Dynamic Vapor Sorption (DVS), Optical Microscope, Scanning Electron Microscope (SEM), Particle Size Analyzer and HPLC.

Interpret thermal, spectroscopic, and chromatographic data to guide excipient and formulation selection.

Integrate solid-state data (polymorphs, salts, amorphous forms) into formulation decisions.

Record all details of experiments and analytical data Write high quality weekly and final reports Routinely present the project results Follow the safety rules and housekeeping principles to ensure all working areas are clean and safe Other responsibilities as assigned Education & Experience PhD or MSc, in pharmaceutical sciences, chemistry, chemical engineering, physics, or related field.





Minimum 5 years of hands-on experience inpreformulation and early formulation development.

Demonstrated experience withtox-enabling formulations, includinglipid-based systems.

Company Overview Solid State Pharma Inc. (SSPI) is a leading pharmaceutical research organization specializing in preformulation and crystallization engineering.

We provide endtoend expertise in solidstate development, including polymorph, salt, and cocrystal screening, as well as crystallization process design, optimization, and scaleup.

Our success is built on a unique integration of crystallization fundamentals, deep solidform science, and years of handson experience supported by advanced highthroughput methodologies.

This combination allows us to deliver rapid, reliable, and scientifically rigorous solutions to complex solidstate challenges. SSPIs research capabilities span a wide range of critical development areas, including: pharmaceutical crystallization engineering, polymorph, salt, and cocrystal screening, preformulation, chiral resolution, polymorph quantification, conversion of amorphous materials to crystalline solids, chemical and crystallization process modeling, size reduction and milling and solid state analytical services.

We partner with pharmaceutical companies around the world to help them fully understand and control the solidstate landscape of their drug candidates, providing toxicologyenabling formulation support that leads to more robust development pathways and improved product performance.

Closing Date Open until filled.

📌 Preformulation Scientist (Halifax Regional Municipality)
🏢 Solid State Pharma
📍 Halifax Regional Municipality