Principal Clinical Scientist (AI Training) About The Role What if your years of clinical trial expertise could directly shape how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research — ensuring the clinical data powering next-generation AI systems meets the standards you'd expect in a real-world regulatory submission. This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms.

No AI background required — just deep expertise in clinical trial design and regulatory-grade data interpretation.

Organization: Alignerr

Type: Hourly Contract

Location: Remote

Commitment: 10–40 hours/week What You'll Do Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training

Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance

Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations (FDA, EMA, or equivalent)

Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes

Help establish quality standards for how AI understands and evaluates real-world clinical evidence





Work independently and asynchronously — fully on your own schedule Who You Are Senior-level experience designing clinical trial protocols for regulatory submission

Deep expertise interpreting clinical data for agencies such as FDA, EMA, or equivalent regulatory bodies

Strong command of clinical research methodology, biostatistics, or translational science

Naturally rigorous and detail-oriented — you hold clinical data to a high standard

Comfortable working independently and delivering structured, well-reasoned expert feedback

No prior AI or tech experience required Nice to Have Prior experience with data annotation, data quality assessment, or evaluation systems

Background in pharmacology, epidemiology, or health outcomes research

Familiarity with AI tools or clinical informatics platforms as an end user

Experience working across multiple therapeutic areas or regulatory jurisdictions Why Join Us Work directly on frontier AI systems shaping the future of clinical and biomedical research

Fully remote and versatile — work when and where it suits you

Freelance autonomy with the structure of meaningful, expert-level work

Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale

Collaborate with leading AI research teams and labs on the cutting edge of the field

Potential for ongoing work and contract extension as new projects launch

📌 Principal Clinical Scientist (Toronto)
🏢 Alignerr
📍 Toronto